开云电竞-欧盟评估非转基因黑曲霉菌株DP

欧盟评估非转基因黑曲霉菌株DP-Azh100出产的葡聚糖1，4-α-葡萄糖苷酶的平安性时候：2024-11-14 10:32来历：食物火伴网作者： 泽夕 焦点提醒：2024年11月13日，欧盟食物平安局就一种葡聚糖1，4-α-葡萄糖苷酶（glucan-1,4-α-glucosidase）的平安性评价发布定见。 食物火伴网讯 2024年11月13日，欧盟食物平安局就一种葡聚糖1，4- -葡萄糖苷酶（glucan-1,4- -glucosidase）的平安性评价发布定见。 据领会，这类食物酶是由非转基因黑曲霉菌株DP-Azh100出产的，旨在用在4种食物出产进程。 颠末评估，专家小组认为，在预期的利用前提下，不克不及解除饮食表露引发过敏反映的风险，但这类环境产生的可能性很低。按照所供给的数据，评估小组得出结论，这类食物酶在预期利用前提下不会引发平安问题。部门原文报导以下： The food enzyme glucan-1,4- -glucosidase (4- -d-glucan glucohydrolase; EC 3.2.1.3) is produced with the non-genetically modified Aspergillus niger strain DP-Azh100 by Genencor International B.V. It was considered free from viable cells of the production organism. The food enzyme is intended to be used in four food manufacturing processes. Since residual amounts of total organic solids (TOS) are removed in two processes, dietary exposure was calculated only for the two remaining processes. It was estimated to be up to 1.390 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level at the highest dose tested of 1000 mg TOS/kg bw per day, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 719. A search for the homology of the amino acid sequence of the food enzyme to known allergens was made and one match to a respiratory allergen was found. Known sources of food allergens were used in the food enzyme manufacturing process. The Panel considered that the risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use. 本文由食物火伴网食物资讯中间编纂，有任何疑问，请联系news@foodmate.net。